During the present examine, BB-22 and BB-22 3-carboxyindole in reliable human urine specimens have been quantified for The 1st time by a sensitive LC–QTRAP tandem mass spectrometry (MS/MS) system that was applied almost in a similar way for 5F-PB-22 and other six SCs in human urine specimens [six, seven] and 5F-NNEI in human serum and urine speci